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・ MT-45
・ MT-50 Multitouch Table
・ MT-55
・ MT-ATP6
・ MT-ATP8
・ MT-CYB
・ MT-Energie
・ MT-LB
・ MT-LBu
・ MT-ND1
・ MT-ND2
・ MT-ND3
・ MT-ND4
・ MT-ND4L
・ MT-ND5
MT-ND6
・ MT-Propeller
・ MT-RNR1
・ MT-RNR2
・ Mt-SNP
・ MT-TA
・ MT-TC
・ MT-TD
・ MT-TE
・ MT-TF
・ MT-TG
・ MT-TH
・ MT-TI
・ MT-TK
・ MT-TL1


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MT-ND6 : ウィキペディア英語版
MT-ND6

NADH-ubiquinone oxidoreductase chain 6 is a protein that in humans is encoded by the mitochondrial gene MT-ND6 gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/gene/4541 )〕 The ND6 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain. Variations in the MT-ND6 gene are associated with Leigh's syndrome, Leber's hereditary optic neuropathy (LHON) and dystonia.
==Structure==
The MT-ND6 gene is located in mitochondrial DNA from base pair 14,149 to 14,673.〔 The encoded protein is 18 kDa and composed of 172 amino acids.〔(【引用サイトリンク】 work = Cardiac Organellar Protein Atlas Knowledgebase (COPaKB) )〕 MT-ND6 is one of seven mitochondrially-encoded subunits of the enzyme NADH dehydrogenase (ubiquinone). Also known as Complex I, it is the largest of the respiratory complexes. The structure is L-shaped with a long, hydrophobic transmembrane domain and a hydrophilic domain for the peripheral arm that includes all the known redox centres and the NADH binding site. MT-ND6 and the rest of the mitochondrially encoded subunits are the most hydrophobic of the subunits of Complex I and form the core of the transmembrane region.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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