翻訳と辞書 Words near each other ・ Mt William North Mining Project ・ MT Zafirah hijacking ・ MT-03 ・ MT-45 ・ MT-50 Multitouch Table ・ MT-55 ・ MT-ATP6 ・ MT-ATP8 ・ MT-CYB ・ MT-Energie ・ MT-LB ・ MT-LBu ・ MT-ND1 ・ MT-ND2 ・ MT-ND3 ・ MT-ND4 ・ MT-ND4L ・ MT-ND5 ・ MT-ND6 ・ MT-Propeller ・ MT-RNR1 ・ MT-RNR2 ・ Mt-SNP ・ MT-TA ・ MT-TC ・ MT-TD ・ MT-TE ・ MT-TF ・ MT-TG ・ MT-TH Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク MT-ND4 ： ウィキペディア英語版 MT-ND4 NADH-ubiquinone oxidoreductase chain 4 is a protein that in humans is encoded by the mitochondrial gene MT-ND4.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4538 )〕 The ND4 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain. Variations in the MT-ND4 gene are associated with age-related macular degeneration (AMD), Leber's hereditary optic neuropathy (LHON), mesial temporal lobe epilepsy (MTLE) and cystic fibrosis.〔〔〔〔 ==Structure== MT-ND4 is located in mitochondrial DNA from base pair 10,760 to 12,137.〔 The MT-ND4 gene produces a 52 kDa protein composed of 459 amino acids.〔(【引用サイトリンク】 work = Cardiac Organellar Protein Atlas Knowledgebase (COPaKB) )〕 MT-ND4 is one of seven mitochondrially-encoded subunits of the enzyme NADH dehydrogenase (ubiquinone). Also known as Complex I, it is the largest of the respiratory complexes. The structure is L-shaped with a long, hydrophobic transmembrane domain and a hydrophilic domain for the peripheral arm that includes all the known redox centres and the NADH binding site. MT-ND4 and the rest of the mitochondrially encoded subunits are the most hydrophobic of the subunits of Complex I and form the core of the transmembrane region.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「MT-ND4」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.