翻訳と辞書
Words near each other
・ IReview
・ Ireviken event
・ Irevna
・ Irewe
・ Irewole
・ IREX
・ Irezumi
・ IRF
・ IRF1
・ IRF2
・ IRF3
・ IRF4
・ IRF5
・ IRF6
・ IRF7
IRF8
・ IRF9
・ Irfan
・ Irfan (actor)
・ Irfan (band)
・ Irfan (disambiguation)
・ Irfan (name)
・ Irfan Abidi
・ Irfan Ahmed
・ Irfan Alam
・ Irfan Ashraf
・ Irfan Bachdim
・ Irfan Bakti Abu Salim
・ Irfan Bhatti
・ Irfan Bhatti (cricketer, born 1964)


Dictionary Lists
翻訳と辞書 辞書検索 [ 開発暫定版 ]
スポンサード リンク

IRF8 : ウィキペディア英語版
IRF8

Interferon regulatory factor 8 (IRF8) also known as interferon consensus sequence-binding protein (ICSBP), is a protein that in humans is encoded by the ''IRF8'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3394 )〕 IRF8 is a transcription factor that plays critical roles in the regulation of lineage commitment and in myeloid cell maturation including the decision for a common myeloid progenitor (CMP) to differentiate into a monocyte precursor cell.
== Function ==
Interferon Consensus Sequence-binding protein (ICSBP) is a transcription factor of the interferon regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-α and IFN-β. IRF family proteins also control expression of IFN-α and IFN-β-regulated genes that are induced by viral infection.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「IRF8」の詳細全文を読む



スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース

Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.