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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Toceranib ： ウィキペディア英語版 Toceranib Toceranib is a receptor tyrosine kinase inhibitor and is used in the treatment of canine mast cell tumor also called mastocytoma. Together with masitinib (Kinavet (US)/Masivet (EU/ROW) by AB Science), toceranib is the only dog-specific anti-cancer drug〔( CBS News FDA Approves First-Ever Dog Cancer Drug )〕 approved by the U.S. Food and Drug Administration.〔( FDA NEWS RELEASE )〕 It is marketed as Palladia as its phosphate salt, toceranib phosphate (INN) by Pfizer. It was developed by SUGEN as SU11654,〔(In Trials for New Cancer Drugs, Family Pets Are Benefiting, Too, New York Times )〕 a sister compound to sunitinib, which was later approved for human therapies. Toceranib is likely to act mostly through inhibition of the kit tyrosine kinase, though it may also have an anti-angiogenic effect. ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Toceranib」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.