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masitinib : ウィキペディア英語版
masitinib

Masitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.〔Information about (Masivet ) at the European pharmacy agency website〕 Since its introduction in November 2008 it has been distributed under the commercial name Masivet. It has been available in Europe since the second part of 2009. In the USA it is distributed under the name Kinavet and has been available for veterinaries since 2011.
Masitinib is being studied for several human conditions including cancers. It is used in Europe to fight orphan diseases.〔(Orphan designation for Masitinib ) at the European pharmacy agency website〕
==Mechanism of action==
Masitinib inhibits the receptor tyrosine kinase c-Kit which is displayed by various types of tumour.〔 It also inhibits the platelet derived growth factor receptor (PDGFR) and fibroblast growth factor receptor (FGFR).

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「masitinib」の詳細全文を読む



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