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Tcelna : ウィキペディア英語版
Tcelna




Tcelna (formerly known as "Tovaxin") is a novel anti-T cell therapeutic vaccine with potential use in treating multiple sclerosis (MS), being developed by Opexa Therapeutics (formerly known as PharmaFrontiers) in The Woodlands, Texas.
==Method of Action==
The proposed mechanism parallels that of autologous cancer vaccines, but instead of modifying cancerous cells, Tcelna consists of attenuated autoreactive T cells.
The production of the vaccine takes a patient's own T cells from a blood sample; attenuation of the cells during the vaccine production process renders the cells non-replicating but viable. They will elicit an immune response when injected subcutaneously into the patient, with the immune response directed against those T cells within the patient that are self-reactive with myelin, the sheath that covers the neurons affected in multiple sclerosis. It is hoped that this immune response directed against a specific subset of autoreactive T cells might reduce the number of these autoreactive cells in MS patients.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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