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・ Tchintoulous
・ Tchiressoua Guel
・ Tchirkpambo
・ Tchirozerine
・ Tchirozerine Department
・ Tchitchide
・ Tchitchide Tare
・ Tchitchoa
・ Tchito
・ Tchitondi
・ TCHO
・ Tcho-Tcho
・ Tchoiria
・ Tchokola
・ TCEB1
TCEB2
・ TCEB3
・ Tcell
・ Tcelna
・ TCEP
・ TCExam
・ TCF
・ TCF Bank
・ TCF Bank Stadium
・ TCF Financial Corporation
・ TCF/LEF family
・ TCF12
・ TCF19
・ TCF20
・ TCF21


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TCEB2 : ウィキペディア英語版
TCEB2

Transcription elongation factor B polypeptide 2 is a protein that in humans is encoded by the ''TCEB2'' gene.
== Function ==

This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6923 )

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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