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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Ralfinamide ： ウィキペディア英語版 Ralfinamide Ralfinamide (INN) (code names NW-1029, FCE-26742A, PNU-0154339E) is a multimodal drug which is under investigation by Newron Pharmaceuticals for the treatment of neuropathic pain and other pain conditions such as post-operative dental pain. It has a relatively complex pharmacology, acting as a mixed voltage-gated sodium channel blocker (including Nav1.7),〔〔 N-type calcium channel blocker,〔〔 noncompetitive NMDA receptor antagonist, and monoamine oxidase B inhibitor. It has thus far progressed as far as phase IIb/phase III clinical trials.〔 In 2010 it failed a phase II trial for lower back pain.〔(Newron reports SERENA trial top-line results for ralfinamide )〕 Encouraging Phase II results have been announced for neuropathic pain.〔(Newron Announces Positive Results With Ralfinamide From Phase II Trial in Neuropathic Pain )〕 ==See also== * Safinamide, different fluorine position * Evenamide, structurally-related antipsychotic in development * Lacosamide, used for partial-onset seizures and diabetic neuropathic pain * Ziconotide, FDA approved peptide for chronic neuropathic pain 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Ralfinamide」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.