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・ NLR Air Transport Safety Institute
・ NLR Class 75
・ NLR crane tank
・ NLRB election procedures
・ NLRB v. Columbian Enameling & Stamping Co.
・ NLRB v. Fansteel Metallurgical Corp.
・ NLRB v. Hearst Publications
・ NLRB v. J. Weingarten, Inc.
・ NLRB v. Jones & Laughlin Steel Corp.
・ NLRB v. Mackay Radio & Telegraph Co.
・ NLRB v. Noel Canning
・ NLRB v. Sands Manufacturing Co.
・ NLRB v. Truck Drivers Local 449
・ NLRC3
・ NLRC4
NLRC5
・ NLRP
・ NLRP1
・ NLRP10
・ NLRP11
・ NLRP12
・ NLRP13
・ NLRP14
・ NLRP2
・ NLRP4
・ NLRP5
・ NLRP6
・ NLRP7
・ NLRP8
・ NLRP9


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NLRC5 : ウィキペディア英語版
NLRC5

NLRC5, short for NOD-like receptor family CARD domain containing 5, is an intracellular protein that plays a role in the immune system. NLRC5 is a pattern recognition receptor implicated in innate immunity to viruses potentially by regulating interferon activity.
Recently, NLRC5 has been suggested to play a positive role in the regulation of Major Histocompatibility Class I (MHCI) molecule expression. This aspect of NLRC5 function was further investigated with the help of ''Nlrc5''-deficient mice, which showed reduced MHCI expression in lymphocytes (particularly T, NK and NKT lymphocytes). In lymphocytes, NLRC5 localizes to the nucleus and drives MHCI gene expression by occupying ''H-2D'' and ''H-2K'' gene promoters.〔
In humans, the NLRC5 protein is encoded by the ''NLRC5'' gene. It has also been called NOD27, NOD4, and CLR16.1.
==References==



抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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