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・ Morr Music
・ Morra
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・ Morra (game)
・ Morra De Sanctis
・ Morra, Dongeradeel
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・ Morradoo railway station
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Morphinan
・ Morphine
・ Morphine (band)
・ Morphine (disambiguation)
・ Morphine (film)
・ Morphine 6-dehydrogenase
・ Morphine methylbromide
・ Morphine Suffering
・ Morphine-3-glucuronide
・ Morphine-6-glucuronide
・ Morphine-N-oxide
・ Morphine/naltrexone
・ Morphing
・ Morphini
・ Morphinone


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Morphinan : ウィキペディア英語版
Morphinan

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Morphinan is the prototype chemical structure of a large chemical class of psychoactive drugs, consisting of opiate analgesics, cough suppressants, and dissociative hallucinogens, among others.
== Structure ==
Morphinan has a phenanthrene core structure with the ''A'' ring remaining aromatic and the ''B'' and ''C'' rings being saturated, and an additional nitrogen-containing, six-membered, saturated ring, the ''D'' ring, being attached to carbons 9 and 13 of the core, and with the nitrogen at position 17 of the composite.
Of the major naturally-occurring opiates of the morphinan type—morphine, codeine and thebaine—thebaine has no therapeutic properties (it causes seizures in humans), but it provides a low-cost feedstock for the synthesis of at least four semi-synthetic opiates, including hydrocodone, hydromorphone, oxycodone and oxymorphone, and, perhaps more significantly, the opioid antagonist naloxone.

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