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Luteoma
A luteoma is a tumor that occurs in the ovaries during pregnancy.
It is associated with an increases of sex hormones, primarily progesterone and testosterone. The size of the tumor can range from 1 to 25 cm in diameter, but is usually 6 to 10 cm in diameter and can grow throughout the duration of the pregnancy. However, luteomas are benign and resolve themselves after delivery. This type of tumor is rare with only about 200 documented cases; many of these cases were detected accidentally, so the actual rate of occurrence may be higher. The most obvious symptom of a luteoma is masculinization of the mother and the possible masculinization of the fetus.〔 This occurs because of the release of testosterone by the luteoma. Testosterone is a sex hormone most abundant in men although small amounts are naturally present in women. Testosterone is responsible for the male characteristics such as deepening of the voice, growth of dark hair, and acne. While not life-threatening, the development of male characteristics associated with luteomas can cause visible changes in the mother and can have drastic effects on the formation of the fetus. Luteomas can cause the fetus to be born with an ambiguous sex necessitating a sex to be chosen for the fetus depending on how the parents want to raise the infant.
Luteomas can be associated with female pseudohermaphroditism.
==Presentation==
Women with a luteoma of pregnancy typically don't show any symptoms. Only 36% of women actually show signs of masculinization.〔 These signs include acne, the growth of dark hair (especially on the face), deepening of the voice, temporal balding, and Clitoromegaly.〔 An increase in testosterone levels in the mother doesn't necessarily mean masculinization will occur. During a normal pregnancy, the testosterone level will increase slightly in the first and second trimester, but doubles in the third trimester. The testosterone level also depends on the sex of the fetus; male fetuses cause a bigger increase in testosterone levels than female fetuses.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
■ウィキペディアで「Luteoma」の詳細全文を読む
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