翻訳と辞書 ・ Ly Tong
・ LY-215,840
・ LY-2183240
・ LY-235,959
・ LY-255582
・ LY-272,015
・ LY-293284
・ LY-2940094
・ LY-307,452
・ LY-310762
・ LY-320,135
・ LY-334370
・ LY-341,495
・ LY-344,545
・ LY-367,265
・ LY-379,268
・ LY-404,039
・ LY-404,187
・ LY-487,379
・ LY-503,430
・ LY-60 / FD-60 / PL10
・ Ly-Cilph
・ Ly-Fontaine
・ LY2181308
・ LY294002
・ LY6
・ LY6E
・ LY6G6E
・ LY75
・ LY9
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LY-379,268
LY-379,268 is a drug that is used in neuroscience research, which acts as a potent and selective agonist for the group II metabotropic glutamate receptors (mGluR2/3).
It is derived from the older mGluR group II agonist eglumegad, and led on to the development of the more potent compound LY-404,039, but is still widely used in research itself. LY-379,268 has sedative, neuroprotective, anti-addictive and anticonvulsant effects in animals, and blocks the effects of PCP and DOI, which has led to research into LY-379,268 and similar compounds as antipsychotic drugs for the treatment of schizophrenia.
There are inconsistent findings about an additional activity as a dopamine D2 receptor partial agonist.
==See also==
* HYDIA
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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