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Gem-Difluoroalkene : ウィキペディア英語版 | Gem-Difluoroalkene
Difluoroalkenes are alkenes that have two fluorines on their sp2 carbon. Difluoroalkenes that have the fluorines on the same carbon, a geminal relationship, are called ''gem''-difluoroalkenes. They have a unique reactivity derived from the fluorines. Generally, the alkenes are known to react with electrophiles. But ''gem''-difluoroalkenes can react also with nucleophiles, since their carbon-carbon double bond is electrophilically activated by the two fluorine atoms. By using this characteristic, several fluorine-containing compounds have been prepared. Because of their biological activities and physical properties, ''gem''-difluoroalkene compounds have been attracting much interest in various fields such as medical and agricultural chemistry and material sciences.
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