翻訳と辞書 Words near each other ・ Dock Street Brewing Company ・ Dock Street Dam ・ Dock Street Theatre ・ Dock Sud ・ Dock Tarn ・ Dock Walloper ・ Dock Walsh ・ Dock warrant ・ Dock Work Convention, 1973 ・ Dock, Wharf, Riverside and General Labourers' Union ・ Dock10 ・ Dock11 ・ Dock180 ・ Dock2 ・ Dock3 ・ Dock4 ・ Dock4-Ex49 ・ Dock5 ・ Dock6 ・ Dock7 ・ Dock8 ・ DOCK8 deficiency ・ Dock9 ・ Dockage ・ Dockanema ・ Dockapps ・ Dockendorf ・ Dockendorff Group ・ Dockenfield ・ Docker (disambiguation) Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Dock4 ： ウィキペディア英語版 Dock4 Dock4, (Dedicator of cytokinesis 4) also known as DOCK4, is a large (~190 kDa) protein involved in intracellular signalling networks.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9732 )〕 It is a member of the DOCK-B subfamily of the DOCK family of guanine nucleotide exchange factors (GEFs) which function as activators of small G proteins. Dock4 activates the small G proteins Rac and Rap1. ==Discovery== Dock4 was discovered as a gene product which was disrupted during tumour progression in a murine cancer model-derived osteosarcoma cell line. Subsequent Northern blot analysis revealed high levels of Dock4 expression in skeletal muscle, prostate and ovary as well as lower levels in the heart, placenta and colon. A separate study has reported expression of a Dock4 splice variant (Dock4-Ex49) in the brain, inner ear and eye. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Dock4」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.