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・ Diminution in value
・ Dimethyl phosphorochloridothioate
・ Dimethyl phthalate
・ Dimethyl pimelimidate
・ Dimethyl sulfate
・ Dimethyl sulfide
・ Dimethyl sulfite
・ Dimethyl sulfoxide
・ Dimethyl sulfoxide (data page)
・ Dimethyl telluride
・ Dimethyl terephthalate
・ Dimethyl tetrachloroterephthalate
・ Dimethyl trisulfide
・ Dimethyl-4-phenylenediamine
・ Dimethyl-sulfide monooxygenase
Dimethylacetamide
・ Dimethylallyl pyrophosphate
・ Dimethylallylcistransferase
・ Dimethylallyltranstransferase
・ Dimethylamidophosphoric dichloride
・ Dimethylamidophosphoric dicyanide
・ Dimethylamine
・ Dimethylamine dehydrogenase
・ Dimethylamine-corrinoid protein Co-methyltransferase
・ Dimethylaminopivalophenone
・ Dimethylaminopropionylphenothiazine
・ Dimethylaminopropylamine
・ Dimethylamphetamine
・ Dimethylaniline
・ Dimethylaniline-N-oxide aldolase


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Dimethylacetamide : ウィキペディア英語版
Dimethylacetamide

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Dimethylacetamide (DMA) is the organic compound with the formula CH3C(O)N(CH3)2. This colorless, water-miscible, high boiling liquid is commonly used as a polar solvent in organic synthesis. DMA is miscible with most other solvents, although it is poorly soluble in aliphatic hydrocarbons.
==Synthesis, reactions, applications==
DMA is prepared by the reaction of dimethylamine with acetic anhydride and esters of acetic acid. Dehydration of the salt of dimethylamine and acetic acid also furnishes this compound:
: CH3CO2H·HN(CH3)2 → H2O + CH3CON(CH3)2
The chemical reactions of dimethylacetamide are typical of ''N'',''N''-disubstituted amides. It will hydrolyze in the presence of acids:
: CH3CON(CH3)2 + H2O + HCl → CH3COOH + (CH3)2NH2+Cl
It is however resistant to bases. For this reason DMA is useful solvent for reactions involving strong bases such as sodium hydroxide.
Dimethylacetamide is commonly used as a solvent for fibers (e.g., polyacrylonitrile, spandex) or in the adhesive industry.〔 It is also employed in the production of pharmaceuticals and plasticizers as a reaction medium.
Dimethylacetamide is also used as an excipient in drugs, e.g. in Vumon (teniposide), Busulfex (busulfan) or Amsidine (amsacrine).

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