|
|Section2= |Section3= }} Bromadiolone is a potent anticoagulant rodenticide. It is a second-generation 4-hydroxycoumarin derivative and vitamin K antagonist, often called a "super-warfarin" for its added potency and tendency to accumulate in the liver of the poisoned organism. When first introduced to the UK market in 1980, it was effective against the populations that had become resistant to the first generation anticoagulants. The product may be used both indoors and outdoors for rats and mice. == Toxicity == Bromadiolone can be absorbed through the digestive tract, through the lungs, or through skin contact. The pesticide is generally given orally.〔(Bromadiolone )〕 The substance is a vitamin K antagonist. The lack of vitamin K in the circulatory system reduces blood clotting and will cause death due to internal hemorrhaging.〔 Poisoning doesn't show up for 24 to 36 hours after poison is eaten and often it may take 2–5 days for the signs to show up. Following are acute values for various animals (mammals):〔 * rats 1.125 mg/kg b.w. * mice 1.75 mg/kg b.w. * rabbits 1 mg/kg b.w. * dogs > 10 mg/kg b.w. (oral MTD)〔(The Veterinarian’s Guide to accidental rodenticide ingestion by dogs & cats )〕 * cats > 25 mg/kg b.w. (oral MTD)〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Bromadiolone」の詳細全文を読む スポンサード リンク
|