翻訳と辞書 Words near each other ・ Argilloberyx ・ Argillochelys ・ Argillophora ・ Argilly ・ Argiloborus ・ Argilophilus ・ Argilos ・ Argimiro España ・ Argimusco ・ Argin ・ Argina ・ Argina amanda ・ Argina astrea ・ Argina, Armenia ・ Arginae ・ Arginase ・ Arginbaatar ・ Arginia ・ Arginine ・ Arginine (data page) ・ Arginine 2-monooxygenase ・ Arginine alphaketoglutarate ・ Arginine and proline metabolism ・ Arginine carboxypeptidase ・ Arginine catabolic mobile element ・ Arginine decarboxylase ・ Arginine deiminase ・ Arginine glutamate ・ Arginine kinase ・ Arginine N-succinyltransferase Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Arginase ： ウィキペディア英語版 Arginase Arginase (, ''arginine amidinase'', ''canavanase'', ''L-arginase'', ''arginine transamidinase'') is a manganese-containing enzyme. The reaction catalyzed by this enzyme is: arginine + H2O → ornithine + urea. It is the final enzyme of the urea cycle. It is ubiquitous to all domains of life. == Structure and function == Arginase belong to the ureohydrolase family of enzymes. Arginase catalyzes the fifth and final step in the urea cycle, a series of biochemical reactions in mammals during which the body disposes of harmful ammonia. Specifically, arginase converts L-arginine into L-ornithine and urea. Mammalian arginase is active as a trimer, but some bacterial arginases are hexameric. The enzyme requires a two-molecule metal cluster of manganese in order to maintain proper function. These Mn2+ ions coordinate with water, orientating and stabilizing the molecule and allowing water to act as a nucleophile and attack L-arginine, hydrolyzing it into ornithine and urea.〔 In most mammals, two isozymes of this enzyme exist; the first, Arginase I, functions in the urea cycle, and is located primarily in the cytoplasm of the liver. The second isozyme, Arginase II, has been implicated in the regulation of the arginine/ornithine concentrations in the cell. It is located in mitochondria of several tissues in the body, with most abundance in the kidney and prostate. It may be found at lower levels in macrophages, lactating mammary glands, and brain. The second isozyme may be found in the absence of other urea cycle enzymes. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Arginase」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.