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Amfecloral : ウィキペディア英語版
Amfecloral

Amfecloral (INN), also known as amphecloral (USAN), is a stimulant drug of the phenethylamine and amphetamine chemical classes that was used as an appetite suppressant under the trade name Acutran, but is now no longer marketed. It acts as a prodrug which splits to form amphetamine and chloral hydrate, similarly to clobenzorex and related compounds, except that the ''N''-substituent in this case yields a compound that is active in its own right. The chloral hydrate metabolite is a gabaminergic sedative/hypnotic, and would in theory counteract some of the stimulant effects of the amphetamine metabolite. This would produce an effect similar to the amphetamine/barbiturate combinations previously used in psychiatric medications.
Amfecloral can be prepared by the reaction of amphetamine with chloral hydrate.〔C. Cavallito, (1960)〕〔Chem. Abstr., 54: 9846c (1966)〕
== See also ==

*Amphetaminil
* Amphetamine
* Clobenzorex
* Desbutal

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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