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・ Alarm in den Bergen
・ Alarm in Peking
・ Alarm in the Circus
・ Alarm indication signal
・ Alarm management
・ Alarm monitoring center
・ Alarm sensor
・ Alarm signal
・ Alarm Will Sound
・ Alarm-class torpedo gunboat
・ Alarm.com
・ Alarma Records
・ Alarmel Valli
・ AlarmForce
・ Alarmism
Alarmone
・ Alarms in the Heart
・ Alarms on submarines of the United States Navy
・ Alarnatha Mandira
・ Alarobia
・ Alarobia Bemaha
・ Alarodian languages
・ ALARP
・ Alarsite
・ Alarsky District
・ Alarud
・ Alarum (band)
・ Alarums and Excursions
・ Alaryngeal speech
・ Alaró


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Alarmone : ウィキペディア英語版
Alarmone

Alarmone is an intracellular signal molecule that is produced due to harsh environmental factors. They regulate the gene expression at transcription level. Alarmones are produced in high concentrations when harsh environmental factors occur in bacteria and plants, such as lack of amino acids to produce proteins. Stringent factors take uncharged tRNA and convert it to an alarmone. Guanosine-5'-triphosphate (GTP) is then converted to 5´-diphosphate 3´-diphosphate guanosine (ppGpp), the archetypical alarmone. ppGpp will bind to RNA polymerase β and β´subunits, changing promoter preference. It will decrease rRNA and other genes transcription but will increase transcription of genes involved in aminoacid biosynthesis and metabolisms involved in famine.
==Notes==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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