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|Section2= |Section3= }} Terpyridine (2,2';6',2"-terpyridine, often abbreviated to terpy or tpy) is a heterocyclic compound derived from pyridine. It is a colourless or white solid that is soluble in most organic solvents. The compound is mainly used as a ligand in coordination chemistry. ==Synthesis== Terpyridine was first synthesized by G. Morgan and F. H. Burstall in 1932 by the oxidative coupling of pyridines. This method, however, proceeded in low yields. More efficient syntheses have since been described, mainly starting from 2-acetylpyridine.〔Hofmeier, H.; Schubert, U. S. "Recent developments in the supramolecular chemistry of terpyridine-metal complexes" Chem. Soc. Rev. 2004, 33, 373. 〕 One method produces an enaminone by the reaction of 2-acetylpyridine with N,N-dimethylformamide dimethyl acetal.〔Donald L. Jameson, Lisa E. Guise "2,2:6,2’-Terpyridine" Inorganic Syntheses 1998, vol. 32, pp. 46–50. 〕 The base-catalyzed reaction of 2-acetylpyridine with carbon disulfide followed by alkylation with methyl iodide gives C5H4NCOCH=C(SMe)2. Condensation of this species with 2-acetylpyridine forms the related 1,5-diketone, which condenses with ammonium acetate to form a terpyridine. Treatment of this derivative with Raney nickel remove the thioether group. Other methods have been developed for the synthesis of terpyridine and its substituted derivatives.〔Kamata, K., Suzuki, A., Nakai, Y., Nakazawa, H., "Catalytic Hydrosilylation of Alkenes by Iron Complexes Containing Terpyridine Derivatives as Ancillary Ligands", Organometallics 2012, 31, 3825. 〕 Substituted terpyridines are also synthesized from palladium-catalyzed cross-coupling reactions. It can be prepared from bis-triazinyl pyridine. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「terpyridine」の詳細全文を読む スポンサード リンク
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