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|Section2= |Section3= }} Punicalagin is an ellagitannin, a type of phenolic compounds. It is found in forms alpha and beta in pomegranates (''Punica granatum''), in ''Terminalia catappa'' and ''Terminalia myriocarpa'', and in ''Combretum molle'', the velvet bushwillow, is a plant species found in South Africa. These three genera are all Myrtales and the last two are both Combretaceae. == Health effects == Punicalagins are the largest molecule found intact in rat plasma after oral ingestion〔Cerda et al. Eur J Nutr. 2003 Jan;42(1), pp. 18-28〕 and were found to show no toxic effects in rats who were given a 6% diet of punicalagins for 37 days.〔Cerda et al. J. Agric. Food Chem. 2003, 51, pp. 3493-3501〕 Punicalagins are also found to be the major component responsible for pomegranate juice's antioxidant activity.〔Gil et al. J Agric Food Chem 2000 48 (10), pp. 4581-4589〕 Punicalagin is water-soluble and has high bioavailability. They are known to hydrolyze into smaller phenolic compounds such as ellagic acid in vivo where one potential mechanism is hydrolysis across the mitochondrial membrane of cultured human colon cells.〔Seeram et al. Clin Chim Acta. 2004 Oct;348(1-2), pp. 63-68〕〔Larrosa et al. J Nutr Biochem. 2006 Sep;17(9), pp. 611-625〕 It is a highly active carbonic anhydrase inhibitor. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「punicalagin」の詳細全文を読む スポンサード リンク
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