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pseudouridine : ウィキペディア英語版
pseudouridine

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Pseudouridine (abbreviated by the Greek letter psi- Ψ) is the ''C''-glycoside isomer of the nucleoside uridine, and it is the most prevalent of the over one hundred different modified nucleosides found in RNA. Ψ is found in all species and in many classes of RNA.
Ψ is formed by enzymes called Ψ synthases, which post-transcriptionally isomerize specific uridine residues in RNA in a process termed ''pseudouridylation''.
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It is commonly found in tRNA, associated with thymidine and cytosine in the TΨC arm and is one of the invariant regions of tRNA.The function of it is not very clear, but it is expected to play a role in association with aminoacyl transferases during their interaction with tRNA, and hence in the initiation of translation. Recent studies suggest it may offer protection from radiation.
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==See also==

*Pseudouridine kinase
*TRNA-pseudouridine synthase

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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