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Primaquine (or primaquine phosphate) is a medication used in the treatment of malaria and ''Pneumocystis'' pneumonia. It is a member of the 8-aminoquinoline group of drugs that includes tafenoquine and pamaquine. Primaquine was first synthesised by Robert Elderfield of Columbia University in the 1940s. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. ==Medical uses== Primaquine is mainly used to treat ''P. vivax'' or ''P. ovale'' malaria, specifically to clear the dormant liver forms of these parasites (hypnozoites) once the parasite has been eliminated from the bloodstream. This requires a 14-day course of primaquine. The process of clearing the hypnozoites is termed radical cure (as opposed to simply clearing the blood of parasites). If primaquine is not administered to patients with proven ''P. vivax'' or ''P. ovale'' infection, a very high likelihood of relapse exists for weeks or months (sometimes years). The interaction between primaquine and quinine or chloroquine is thought to improve the rate of radical cure. Whether other antimalarials such as mefloquine are likewise able to potentiate the effect of primaquine is not known. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「primaquine」の詳細全文を読む スポンサード リンク
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