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Phototoxicity, also called photoirritation, is a chemically induced skin irritation, requiring light, that does not involve the immune system. It is a type of photosensitivity.〔 The skin response resembles an exaggerated sunburn. The involved chemical may enter into the skin by topical administration or it may reach the skin via systemic circulation following ingestion or parenteral administration. The chemical needs to be "photoactive", which means that when it absorbs light, the absorbed energy produces molecular changes that cause toxicity. Many synthetic compounds, including drug substances like tetracyclines or fluoroquinolones, are known to cause these effects. Surface contact with some such chemicals causes photodermatitis; many plants cause phytophotodermatitis. Light-induced toxicity is a common phenomenon in humans; however, it also occurs in other animals. ==Scientific background== A phototoxic substance is a chemical compound which becomes toxic when exposed to light. *Some medicines: tetracycline antibiotics, sulfonamides, amiodarone, quinolones *Many cold pressed citrus essential oils such as bergamot oil *Some plant juices: parsley, lime, and Giant hogweed *Others: psoralen 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「phototoxicity」の詳細全文を読む スポンサード リンク
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