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penicillin : ウィキペディア英語版
penicillin

Penicillin (PCN or pen) is a group of antibiotics which include penicillin G (intravenous use), penicillin V (oral use), procaine penicillin, and benzathine penicillin (intramuscular use). They are derived from ''Penicillium'' fungi.〔(Penicillin at the Free Dictionary )〕

Penicillin antibiotics were among the first medications to be effective against many bacterial infections caused by staphylococci and streptococci. Penicillins are still widely used today, though many types of bacteria have developed resistance following extensive use. All penicillins are β-lactam antibiotics.

About 10% of people report that they are allergic to penicillin; however, 90% of this group are not actually allergic.〔 Serious allergies only occur in about 0.03%.
Penicillin was discovered in 1928 by Scottish scientist Alexander Fleming.〔(【引用サイトリンク】url=http://www.acs.org/content/acs/en/education/whatischemistry/landmarks/flemingpenicillin.html )〕 People began using it to treat infections in 1942. There are several enhanced penicillin families which are effective against additional bacteria; these include the antistaphylococcal penicillins, aminopenicillins and the antipseudomonal penicillins.
==Medical uses==
The term "penicillin" is often used generically to refer to benzylpenicillin (penicillin G, the original penicillin found in 1928), procaine benzylpenicillin (procaine penicillin), benzathine benzylpenicillin (benzathine penicillin), and phenoxymethylpenicillin (penicillin V). Procaine penicillin and benzathine penicillin have the same antibacterial activity as benzylpenicillin but act for a longer period of time. Phenoxymethylpenicillin is less active against gram-negative bacteria than benzylpenicillin.〔
〕〔
〕 Benzylpenicillin, procaine penicillin and benzathine penicillin are given by injection (parenterally), but phenoxymethylpenicillin is given orally.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「penicillin」の詳細全文を読む



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