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Neurosyphilis is an infection of the brain or spinal cord caused by the spirochete ''Treponema pallidum''. It usually occurs in people who have had chronic, untreated syphilis, usually about 10 to 20 years after first infection〔 and develops in about 25%–40% of persons who are not treated.〔 The United States' Centers for Disease Control and Prevention (CDC) advises that neurosyphilis can occur at any stage of a syphilis infection.〔 ==Signs and symptoms== Neurosyphilis has four different forms: asymptomatic, meningovascular, tabes dorsalis, and general paresis.〔 In rare instances, active neurosyphilis can mimic Alzheimer's disease.〔 Symptoms of neurosyphilis include, but are not limited to the following:〔〔 *Abnormal gait *Blindness *Confusion, disorientation *Sudden personality changes *Changes in mental stability *Dementia *Depression *Headache *Incontinence *Irritability *Memory problems *Mood disturbances *Numbness in the toes, feet, or legs *Poor concentration *Psychosis〔 *Seizures *Neck stiffness *Tremors *Visual disturbances. There may be the sign of Argyll Robertson pupils, which are bilateral small pupils that constrict when the patient focuses on a near object, but do not constrict when exposed to bright light. *Muscle weakness Upon further diagnostic workup, the following signs may be present: *Abnormal reflexes *Muscle atrophy *Muscle contractions 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「neurosyphilis」の詳細全文を読む スポンサード リンク
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