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grayanotoxin
Grayanotoxins are a group of closely related toxins found in rhododendrons and other plants of the family ''Ericaceae''. They can be found in honey made from their nectar and cause a very rare poisonous reaction called grayanotoxin poisoning, honey intoxication, or rhododendron poisoning. Grayanotoxin I (see below) is also known as andromedotoxin, acetylandromedol, rhodotoxin and asebotoxin; the systematic chemical name is: ''grayanotaxane-3,5,6,10,14,16-hexol 14-acetate''. Grayanotoxins are named after ''Leucothoe grayana'', a plant species from Japan, which is in turn named after 19th century American botanist Asa Gray.
==Chemical structure==
Ac = acetyl
Grayanotoxins are polyhydroxylated cyclic diterpenes. They bind to specific sodium ion channels in cell membranes, the receptor sites involved in activation and inactivation. The grayanotoxin prevents inactivation, leaving excitable cells depolarized.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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