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faldaprevir
Faldaprevir (formerly BI 201335) is an experimental drug for the treatment of hepatitis C. It is being developed by Boehringer-Ingelheim and is currently in Phase III trials.〔(Efficacy and Safety of BI 201335 (Faldaprevir) in Combination With Pegylated Interferon-alpha and Ribavirin in Treatment-naïve Genotype 1 Hepatitis C Infected Patients (STARTverso 1) ). Cliicaltrials.gov. March 6, 2013.〕
Faldaprevir is a hepatitis C virus protease inhibitor.
Faldaprevir is being tested in combination regimens with pegylated interferon and ribavirin, and in interferon-free regimens with other direct-acting antiviral agents including BI 207127.
Data from the SOUND-C2 study, presented at the 2012 AASLD Liver Meeting, showed that a triple combination of faldaprevir, BI 207127, and ribavirin performed well in HCV genotype 1b patients.〔(Interferon-free hepatitis C treatment with faldaprevir proves safe and effective in people with cirrhosis ). Alcorn, K. Aidsmap.com. 20 November 2012.〕 Efficacy fell below 50%, however, for dual regimens without ribavirin and for genotype 1a patients.
==References==
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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