翻訳と辞書 Words near each other ・ "O" Is for Outlaw ・ "O"-Jung.Ban.Hap. ・ "Ode-to-Napoleon" hexachord ・ "Oh Yeah!" Live ・ "Our Contemporary" regional art exhibition (Leningrad, 1975) ・ "P" Is for Peril ・ "Pimpernel" Smith ・ "Polish death camp" controversy ・ "Pro knigi" ("About books") ・ "Prosopa" Greek Television Awards ・ "Pussy Cats" Starring the Walkmen ・ "Q" Is for Quarry ・ "R" Is for Ricochet ・ "R" The King (2016 film) ・ "Rags" Ragland ・ ! (album) ・ ! (disambiguation) ・ !! ・ !!! ・ !!! (album) ・ !!Destroy-Oh-Boy!! ・ !Action Pact! ・ !Arriba! La Pachanga ・ !Hero ・ !Hero (album) ・ !Kung language ・ !Oka Tokat ・ !PAUS3 ・ !T.O.O.H.! ・ !Women Art Revolution Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク dabrafenib ： ウィキペディア英語版 dabrafenib Dabrafenib (trade name Tafinlar) is a drug for the treatment of cancers associated with a mutated version of the gene ''BRAF''. Dabrafenib acts as an inhibitor of the associated enzyme B-Raf, which plays a role in the regulation of cell growth. Dabrafenib has clinical activity with a manageable safety profile in clinical trials of phase 1 and 2 in patients with BRAF(V600)-mutated metastatic melanoma. The Food and Drug Administration approved dabrafenib as a single agent treatment for patients with BRAF V600E mutation-positive advanced melanoma on May 30, 2013. Clinical trial data demonstrated that resistance to dabrafinib and other BRAF inhibitors occurs within 6 to 7 months. To overcome this resistance, the BRAF inhibitor dabrafenib was combined with the MEK inhibitor trametinib.〔 As a result of this research, on January 8, 2014, the FDA approved the combination of dabrafenib and trametinib for the treatment of patients with BRAF V600E/K-mutant metastatic melanoma. ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「dabrafenib」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.