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carnosine : ウィキペディア英語版
carnosine

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Carnosine (''beta''-alanyl-L-histidine) is a dipeptide of the amino acids beta-alanine and histidine. It is highly concentrated in muscle and brain tissues.
''Carnosine'' and carnitine were discovered by Russian chemist V.Gulevich. Researchers in Britain, South Korea, Russia and other countries have shown that carnosine has a number of antioxidant properties that may be beneficial. Carnosine has been proven to scavenge reactive oxygen species (ROS) as well as alpha-beta unsaturated aldehydes formed from peroxidation of cell membrane fatty acids during oxidative stress. Carnosine is also a zwitterion, a neutral molecule with a positive and negative end.
Like carnitine, carnosine is composed of the root word ''carn'', meaning ''flesh'', alluding to its prevalence in animal protein. A vegetarian (especially vegan) diet is deficient in adequate carnosine, compared to levels found in a standard diet.
Carnosine can chelate divalent metal ions.
Carnosine can increase the Hayflick limit in human fibroblasts, as well as appearing to reduce the telomere shortening rate. Carnosine is also considered as a geroprotector.
==Biochemistry==
In humans, postprandial blood plasma levels of carnosine is zero within several hours of red meat consumption, implying that carnosine is rapidly metabolized considering the slow digestion of animal protein. This denotes a significantly short-lived impact when carnosine is taken in the form of a dietary supplement, though the latent cascade of effects from supplementing carnosine may still prove beneficial.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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