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axon : ウィキペディア英語版
axon

An axon (from Greek ἄξων ''áxōn'', axis), is a long, slender projection of a nerve cell, or neuron, that typically conducts electrical impulses away from the neuron's cell body. Myelinated axons are known as nerve fibers. The function of the axon is to transmit information to different neurons, muscles and glands. In certain sensory neurons (pseudounipolar neurons), such as those for touch and warmth, the electrical impulse travels along an axon from the periphery to the cell body, and from the cell body to the spinal cord along another branch of the same axon. Axon dysfunction causes many inherited and acquired neurological disorders which can affect both the peripheral and central neurons.
An axon is one of two types of protoplasmic protrusions that extrude from the cell body of a neuron, the other type being dendrites. Axons are distinguished from dendrites by several features, including shape (dendrites often taper while axons usually maintain a constant radius), length (dendrites are restricted to a small region around the cell body while axons can be much longer), and function (dendrites usually receive signals while axons usually transmit them). All of these rules have exceptions, however.
Some types of neurons have no axon and transmit signals from their dendrites. No neuron ever has more than one axon; however in invertebrates such as insects or leeches the axon sometimes consists of several regions that function more or less independently of each other. Most axons branch, in some cases very profusely.
Axons make contact with other cells—usually other neurons but sometimes muscle or gland cells—at junctions called synapses. At a synapse, the membrane of the axon closely adjoins the membrane of the target cell, and special molecular structures serve to transmit electrical or electrochemical signals across the gap. Some synaptic junctions appear partway along an axon as it extends—these are called ''en passant'' ("in passing") synapses. Other synapses appear as terminals at the ends of axonal branches. A single axon, with all its branches taken together, can innervate multiple parts of the brain and generate thousands of synaptic terminals.
==Anatomy==

Axons are the primary transmission lines of the nervous system, and as bundles they form nerves. Some axons can extend up to one meter or more while others extend as little as one millimeter. The longest axons in the human body are those of the sciatic nerve, which run from the base of the spinal cord to the big toe of each foot. The diameter of axons is also variable. Most individual axons are microscopic in diameter (typically about one micrometer (µm) across). The largest mammalian axons can reach a diameter of up to 20 µm. The squid giant axon, which is specialized to conduct signals very rapidly, is close to 1 millimetre in diameter, the size of a small pencil lead. Axonal arborization (the branching structure at the end of a nerve fiber) also differs from one nerve fiber to the next. Axons in the central nervous system typically show complex trees with many branch points. In comparison, the cerebellar granule cell axon is characterized by a single T-shaped branch node from which two parallel fibers extend. Elaborate arborization allows for the simultaneous transmission of messages to a large number of target neurons within a single region of the brain.
There are two types of axons occurring in the peripheral system and the central nervous system: unmyelinated and myelinated axons.〔 Myelin is a layer of a fatty insulating substance, which is formed by two types of glial cells: Schwann cells ensheathing peripheral neurons and oligodendrocytes insulating those of the central nervous system. Along myelinated nerve fibers, gaps in the myelin sheath known as nodes of Ranvier occur at evenly spaced intervals. The myelination enables an especially rapid mode of electrical impulse propagation called saltatory conduction. Demyelination of axons causes the multitude of neurological symptoms found in the disease multiple sclerosis.
If the brain of a vertebrate is extracted and sliced into thin sections, some parts of each section appear dark and other parts lighter in color. The dark parts are known as grey matter and the lighter parts as white matter. White matter gets its light color from the myelin sheaths of axons: the white matter parts of the brain are characterized by a high density of myelinated axons passing through them, and a low density of cell bodies of neurons. The cerebral cortex has a thick layer of grey matter on the surface and a large volume of white matter underneath: what this means is that most of the surface is filled with neuron cell bodies, whereas much of the area underneath is filled with myelinated axons that connect these neurons to each other.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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