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Valofane
Valofane is a sedative drug structurally related to the barbiturates〔Traversa U, Puppini P, Jacquot C, Vertua R. Effect of an atypical barbiturate, the 2-allophanyl-2-allyl-4-valerolactone (valofan), on exploratory behaviour and brain serotonin concentrations in mice. ''Journal de Pharmacologie''. 1985 Jul-Sep;16(3):279-90.〕 and similar drugs such as primidone. It is metabolised once inside the body to form the barbiturate proxibarbal and is thus a prodrug.〔Lambrey B, Compagnon PL, Jacquot C. Pharmacokinetics of 14C-2-allophanyl-2-allyl -gamma-valero-lactone: a prodrug of proxibarbal in rats. ''European Journal of Drug Metabolism and Pharmacokinetics''. 1981;6(3):161-9.〕 == References == 〔
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