翻訳と辞書 Words near each other ・ Vraj Hindu Temple ・ Vraja Parikrama ・ Vrajesh Hirjee ・ Vrak ・ Vraka ・ Vrakbukta ・ Vrakupovitsa ・ Vrakuňa ・ Vrakúň ・ VRAM ・ Vrams Gunnarstorp Castle ・ Vramshapuh ・ VPS13D ・ VPS18 ・ VPS24 ・ VPS25 ・ VPS26A ・ VPS26B ・ VPS28 ・ VPS29 ・ VPS33A ・ VPS33B ・ VPS35 ・ VPS36 ・ VPS37A ・ VPS39 ・ VPS45 ・ VPS4A ・ VPS4B ・ VPS52 Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク VPS25 ： ウィキペディア英語版 VPS25 Vacuolar protein-sorting-associated protein 25 is a protein that in humans is encoded by the ''VPS25'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84313 )〕 It is a component of the endosome-associated complex ESCRT-II (Endosomal Sorting Complexes Required for Transport protein II). ESCRT (ESCRT-I, -II, -III) complexes orchestrate efficient sorting of ubiquitinated transmembrane receptors to lysosomes via multivesicular bodies (MVBs). ESCRT-II recruits the transport machinery for protein sorting at MVB. In addition, the human ESCRT-II has been shown to form a complex with RNA polymerase II elongation factor ELL in order to exert transcriptional control activity. ESCRT-II transiently associates with the endosomal membrane and thereby initiates the formation of ESCRT-III, a membrane-associated protein complex that functions immediately downstream of ESCRT-II during sorting of MVB cargo. ESCRT-II in turn functions downstream of ESCRT-I, a protein complex that binds to ubiquitinated endosomal cargo. ESCRT-II is a trilobal complex composed of two copies of vps25, one copy of vps22 and the C-terminal region of vps36. The crystal structure of vps25 revealed two winged-helix domains, the N-terminal domain of vps25 interacting with vps22 and vps36. ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「VPS25」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.