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|Section2= |Section3= }} Triazabicyclodecene (1,5,7-Triazabicyclo()dec-5-ene or TBD) is a commercially available bicyclic strong guanidine base (''pKa'' = 25.98 in CH3CN and ''pKa'' = 21.00 in THF). TBD is an organic soluble base which has been used effectively for a variety of base-mediated organic transformations such as:〔Adam Huczynski, Bogumil Brzezinski, "1,5,7-Triazabicyclo()dec-5-ene", e-EROS Encyclopedia of Reagents for Organic Synthesis,John Wiley & Sons, Ltd 2008,〕 * Michael reactions, * Henry (nitroaldol reactions), * Wittig reactions, * Horner-Wadsworth-Emmons reactions, * transesterification reactions, * etherifications, * ring-opening polymerizations (Scheme 1), * tautomerizations and epimerizations * P-C and P-N bond formations, * Knoevenagel condensations, * deprotonation reactions of phenols, carboxylic acids and C-acids (Scheme 2) * Aminolysis of esters,〔Cyrille Sabot, Kanduluru Ananda Kumar, Stéphane Meunier, Charles Mioskowski, "A convenient aminolysis of esters catalyzed by 1,5,7-triazabicyclo()dec-5-ene (TBD) under solvent-free conditions", Tetrahedron Lett., 2007, 3863-3866 〕 It is also known in deprotonated form (at the 7-position), often as a ligand, for instance in Ditungsten tetra(hpp) ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Triazabicyclodecene」の詳細全文を読む スポンサード リンク
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