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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク TXN2 ： ウィキペディア英語版 TXN2 Thioredoxin, mitochondrial also known as thioredoxin-2 is a protein that in humans is encoded by the ''TXN2'' gene on chromosome 22.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/gene/25828 )〕 This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis.〔 ==Structure== As a thioredoxin, TXN2 is a 12-kDa protein characterized by the redox active site Trp-Cys-Gly-Pro-Cys. In its oxidized (inactive) form, the two cysteines form a disulfide bond. This bond is then reduced by thioredoxin reductase and NADPH to a dithiol, which serves as a disulfide reductase. In contrast to TXN1, TXN2 contains a putative N-terminal mitochondrial targeting sequence, responsible for its mitochondria localization, and lacks structural cysteines. Two mRNA transcripts of the ''TXN2'' gene differ by ~330 bp in the length of the 3′-untranslated region, and both are believed to exist in vivo.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「TXN2」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.