TRAF-type zinc finger domain-containing protein 1 is a protein that in humans is encoded by the ''TRAFD1'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10906 )〕
Model organisms have been used in the study of TRAFD1 function. A conditional knockout mouse line, called ''Trafd1tm1a(EUCOMM)Wtsi'' was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists.
Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion.〔〔 〕 Twenty eight tests were carried out on homozygous mutant mice and two significant abnormalities were observed: abnormal spine curvature and atypical peripheral blood lymphocyte parameters. 〔
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
| 翻訳と辞書 : 翻訳のためのインターネットリソース|
Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.