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・ Tapasya (1992 film)
・ Tapasya Nayak Srivastava
・ Tapatalk
・ Tapatan
・ Tapatan with Jay Sonza
・ Tapatapa River
・ Tapatío
・ Tapatío hot sauce
・ Tapauá
・ Tapauá River
・ Tap wrench
・ Tap!
・ Tap, Azerbaijan
・ Tap-Out (Transformers)
・ Tap-Tap (disambiguation)
TAP1
・ TAP2
・ TaPa
・ Tapa
・ Tapa (Filipino cuisine)
・ Tapa (game)
・ Tapa Airfield
・ Tapa Army Base
・ Tapa cloth
・ Tapa Gaccha
・ Tapa Parish
・ Tapa Tchermoeff
・ Tapa, Estonia
・ TAPAAL Model Checker
・ Tapacarí


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TAP1 : ウィキペディア英語版
TAP1

Transporter associated with Antigen Processing 1 is a protein that in humans is encoded by the ''TAP1'' gene.
== Function ==

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6890 )

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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