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Relamorelin
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Relamorelin : ウィキペディア英語版
Relamorelin

Relamorelin (INN, USAN) (developmental code names RM-131, BIM-28131, BIM-28163) is a synthetic, peptidic, centrally penetrant, selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR) which is under development by Rhythm Pharmaceuticals for the treatment of diabetic gastroparesis, chronic idiopathic constipation, and anorexia nervosa. It is a pentapeptide and analogue of ghrelin with improved potency and pharmacokinetics.〔〔 In humans, relamorelin produces increases in plasma growth hormone, prolactin, and cortisol levels,〔 and, like other GHSR agonists, increases appetite.〔 As of June 2015, relamorelin is in phase II clinical trials for diabetic gastroparesis and constipation. The United States Food and Drug Administration (FDA) has granted ] designation to relamorelin for diabetic gastroparesis.
==See also==

* Anamorelin
* Capromorelin
* Examorelin (hexarelin)
* GHRP-6 (SKF-110679)
* Ibutamoren (MK-677)
* Ipamorelin
* Macimorelin
* Pralmorelin (GHRP-2)
* SM-130,686
* Tabimorelin

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Relamorelin」の詳細全文を読む



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