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|Section2= |Section3= }} Quinazoline is a heterocyclic compound made up of two fused six-membered simple aromatic rings, a benzene ring and a pyrimidine ring. Its chemical formula is C8H6N2. Quinazoline is yellow solid. It is isomeric with other naphthyridines including quinoxaline, phthalazine and cinnoline. Derivatives of quinazoline are called quinazolines. Medicinally it has been used in various areas especially as an anti-malarial agent and in cancer treatment. Quinazoline derivatives as quinazolinediones showed activity against murine P388 Leukemia, increased by dimerization.〔Giorgi-Renault, S., Renault J., Baron M., Gebel-Servolles, P., Delic, J., Cros S., Paoletti C., Heterocyclic quinones XIII. Dimerization in the series of 5,8-quinazolinediones: Synthesis and anti tumor effects of bis(4-amino-5,8-quinazolinediones), Chem. Pharm. Bull., 36 (10), 3933-3947 (1988).〕 One example of a compound containing the quinazoline structure is doxazosin mesylate. The ring system is typically prepared by heating 2-acylanilides in the presence of ammonia or amines. ==See also== *Quinazolinone *Niementowski quinazoline synthesis 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Quinazoline」の詳細全文を読む スポンサード リンク
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