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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク ProSavin ： ウィキペディア英語版 ProSavin ProSavin is an experimental drug believed to be of use in the treatment of Parkinson's Disease. It is administered to the striatum in the brain, inducing production of dopamine.〔Oxford BioMedica. (Drug Information Page ). Retrieved on March 29, 2007.〕 It is manufactured by Oxford BioMedica, who plan to start European Phase I and Phase II clinical trials in 2007. Animal trials have been a success, with dopamine levels restored without the side effects associated with other current treatments for Parkinson's,〔Daily Telegraph. (Investor Information ). Retrieved on March 29, 2007.〕 in particular, without the jerky involuntary movements associated with current drugs. ==Mechanism of Action== Prosavin uses Oxford BioMedica's Lentivector delivery system to transfer three genes, aromatic amino acid dopa decarboxylase, tyrosine hydroxylase and GTP-cyclohydrolase 1, to the striatum in the brain, reprogramming transduced cells to secrete dopamine.〔Oxford BioMedica . (Drug Advanced Information Page ). Retrieved on April 5, 2007.〕 http://www.oxfordbiomedica.co.uk/prosavin-r/ 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「ProSavin」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.