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Primodos
Primodos was a hormone-based pregnancy test used in the 1960s and 1970s that consisted of two pills that contained norethisterone (as acetate) and ethinylestradiol.〔Department of Health, ''Hansard'', HL Deb, 26 October 2010, c264W ()〕 It detected pregnancy by inducing menstruation in women who were not pregnant. The presence or absence of menstrual bleeding was then used to determine whether the user was pregnant.〔
First made available for sale in the UK in 1959, it was withdrawn from sale in the UK in 1978.〔(【引用サイトリンク】title=Hormone pregnancy tests )〕
Another hormonal pregnancy test called Duogynon was in use in Germany during the same general time period.〔
== Claims of adverse effects ==
There are disputed claims as to whether Primodos may have been the cause of birth defects.〔〔(【引用サイトリンク】url=http://www.dailymail.co.uk/health/article-1375825/Primodos-causing-deformities-Fresh-challenge-planned-Bayer.html )〕〔(【引用サイトリンク】title=Fresh 'Forgotten Thalidomide' Legal Claim )〕 A review by the Committee on Safety of Medicines in the 1970s concluded that the product should not be used by pregnant women.〔 Litigation in the 1980s regarding these claims ended inconclusively, with proceedings being discontinued, with the court's approval.〔"Jury still out in pregnancy test case", ''New Scientist'', 8 July 1982, page 79〕〔 A review of the matter by the Medicines and Healthcare Products Regulatory Agency in 2014 assessed the studies performed to date, and concluded that it found the evidence for adverse effects to be inconclusive.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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