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・ Pidhaitsi Raion
・ Pidham Hill
・ Pidhiria
・ Pidhirtsi
・ Pidhirtsi Castle
・ Pidhorodne
・ Pidi Tongap
・ Pidichirukku
・ Pidie Jaya Regency
・ Pidie Regency
・ Pidigan, Abra
・ Pidikhtos
・ Pidikittapulli
・ Pidikkaparambu
・ Pidilite Industries
Pidilizumab
・ Pidimgoyya
・ Piding
・ Pidiyum kozhiyum
・ Pidjani
・ Pidjiguiti massacre
・ Pidkamin
・ Pidkamin massacre
・ Pidkova
・ Pidley
・ Pidlissia
・ Pidlissia, Buchach Raion
・ Pidlyssia
・ PIDO
・ Pido Jarencio


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Pidilizumab : ウィキペディア英語版
Pidilizumab

Pidilizumab (formerly CT-011) is a monoclonal antibody developed by CureTech for the treatment of cancer and infectious diseases.〔(Statement On A Nonproprietary Name Adopted By The USAN Council - Pidilizumab ), ''American Medical Association''- needs login.〕 Pidilizumab binds to the PD-1 immune checkpoint molecule. Mechanistically, the binding of pidilizumab to PD-1 results in the attenuation of apoptotic processes in lymphocytes, primarily effector/memory T cells.
==Clinical trials==
It had encouraging results by 2011 from phase II clinical trials for diffuse large B-cell lymphoma.〔(Teva Invests $19M More in CureTech After Positive Phase II DLBCL Data. Sept 2011 )〕 A phase II open-label study in combination for relapsed follicular lymphoma found good results compared to usual response rates. An add-on trial for multiple myeloma is ongoing.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Pidilizumab」の詳細全文を読む



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