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Philanthotoxin : ウィキペディア英語版
Philanthotoxin

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Philanthotoxins are components of the venom of Egyptian solitary wasp ''Philanthus triangulum F'' and four toxins are distinguished (alpha, beta, gamma, delta) among which delta-philanthotoxin (dPTX) is most effective to block glutamate receptors〔Piek T (1982) Comp Biochem Physiol C 72:311-315〕 and especially those quisqualate-sensitive, that is AMPA receptor.〔Clark RB, Donaldson PL, Gration KAF, Lambert JJ, Piek T, Ramsey RL, Spanjer, Usheerwood PNR (1982) Brain Research 241:105-114〕 It has later been shown that dPTX targets calcium permeable AMPA receptor and kainate receptor but not NMDA receptor.〔Jones MJ, Anis NA, Lodge D (1990) Br J Pharmacol 101(4):968-970〕
==References==



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