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Pentastarch is a subgroup of hydroxyethyl starch, with five hydroxyethyl groups out of each 11 hydroxyls, giving it approximately 50% hydroxyethylation. This compares with tetrastarch at 40% and hetastarch at 70% hydroxyethylation, respectively. It is sold under the name Pentaspan and used for fluid resuscitation. It is considered a plasma expander because it remains primarily intravascular after infusion. ==Choice of resuscitation fluid== The choice of fluid (normal saline vs. Ringer's lactate vs. pentaspan) is controversial. Physiologically, fluid with pentaspan stays primarily in the intravascular space: blood plasma. This is different than normal saline, which shifts quickly into the rest of the extracellular compartment. Advocates of pentaspan use believe that: # the primary deficit in fluid resuscitation is intravascular volume loss〔 and # use of normal saline may lead to pulmonary edema, particularly in older patients.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Pentastarch」の詳細全文を読む スポンサード リンク
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