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Palatability is the hedonic reward provided by foods or fluids that are agreeable to the "palate" in regard to the homeostatic satisfaction of nutritional, water, or energy needs.〔Friedman MI, Stricker EM. (1976). The physiological psychology of hunger: a physiological perspective. Psychol Rev. 83(6):409-31. PMID 1005583〕 The palatability of a food or fluid, unlike its flavor or taste, varies with the state of an individual: it is lower after consumption and higher when deprived. Palatability of foods, however, can be learned. It has increasingly been appreciated that this can create a hedonic hunger that is independent of homeostatic needs.〔Lowe MR, Butryn ML. (2007). Hedonic hunger: a new dimension of appetite? Physiol Behav. Jul 24;91(4):432-9. PMID 17531274 〕 ==Brain mechanism== The palatability of a substance is determined by opioid receptor-related processes in the nucleus accumbens and ventral pallidum.〔Wassum KM, Ostlund SB, Maidment NT, Balleine BW. (2009). Distinct opioid circuits determine the palatability and the desirability of rewarding events. Proc Natl Acad Sci U S A. 106:12512–12517 PMID 19597155 〕 The opioid processes involve mu opioid receptors and are present in the rostromedial shell part of the nucleus accumbens〔Peciña S, Berridge KC. (2005). (Hedonic hot spot in nucleus accumbens shell: where do mu-opioids cause increased hedonic impact of sweetness? ) J Neurosci. 14;25(50):11777-86. PMID 16354936 〕 on its spiny neurons.〔Kelley AE, Bakshi VP, Haber SN, Steininger TL, Will MJ, Zhang M. (2002). Opioid modulation of taste hedonics within the ventral striatum. Physiol Behav. 76(3):365-77. PMID 12117573〕 This area has been called the "opioid eating site".〔Peciña S, Berridge KC. (2000).Opioid site in nucleus accumbens shell mediates eating and hedonic 'liking' for food: map based on microinjection Fos plumes. Brain Res. 863(1-2):71-86. PMID 10773195〕 The rewardfulness of consumption associated with palatability is dissociable from desire or incentive value which is the motivation to seek out a specific commodity.〔 Desire or incentive value is processed by opioid receptor-related processes in the basolateral amygdala.〔 Unlike the liking palatability for food, the incentive salience wanting is not downregulated by the physiological consequences of food consumption and may be largely independent of homoeostatic processes influencing food intake.〔Finlayson G, King N, Blundell J. (2008). The role of implicit wanting in relation to explicit liking and wanting for food: implications for appetite control. Appetite. 50(1):120-7. PMID 17655972 〕 Though the wanting of incentive salience may be informed by palatability it is independent and not necessarily reduced to it.〔 It has been suggested that a third system exists that links opioid processes in the two parts of the brain: "Logically this raises the possibility that a third system, with which the accumbens shell, ventral pallidum, and basolateral amygdala are associated, distributes the affective signals elicited by specific commodities across distinct functional systems to control reward seeking... At present we do not have any direct evidence for a system of this kind, but indirect evidence suggests it may reside within the motivationally rich circuits linking hypothalamic and brainstem viscerogenic structures such as the parabrachial nucleus.〔 It has also been suggested that "hedonic hunger" can be driven both in regard to “wanting” and “liking”〔 and that a palatability subtype of neuron may also exist in the basolateral amygdala.〔Fontanini A, Grossman SE, Figueroa JA, Katz DB. (2009). Distinct subtypes of basolateral amygdala taste neurons reflect palatability and reward. J Neurosci. 29(8):2486-95. PMID 19244523〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Palatability」の詳細全文を読む スポンサード リンク
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