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・ PRK Hekari United
・ PRKAA2
・ PRKAB1
・ PRKAB2
・ PRKACA
・ PRKACB
・ PRKACG
・ PRKAG1
・ PRKAG2
・ PRKAG3
・ PRKAR1A
・ PRKAR1B
・ PRKAR2A
・ PRKAR2B
・ PRKCB1
PRKCD
・ PRKCE
・ PRKCG
・ PRKCH
・ PRKCI
・ PRKCQ
・ PRKCSH
・ PRKD2
・ PRKD3
・ PRKG1
・ Prkosava
・ Prkosi
・ Prkovci
・ Prkovići
・ PRKRA


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PRKCD : ウィキペディア英語版
PRKCD

Protein kinase C delta type is an enzyme that in humans is encoded by the ''PRKCD'' gene.
== Function ==

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5580 )〕 Protein kinase C delta is also regulated by phosphorylation on various serine/threonine (e.g. T50, T141, S304, T451, T505, S506, T507, S643, S664) and tyrosine residues including Y311 (by SRC).

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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