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The P3b is a subcomponent of the P300, an event-related potential (ERP) component that can be observed in human scalp recordings of brain electrical activity. The P3b is a positive-going amplitude (usually relative to a reference behind the ear or the average of two such references) peaking at around 300 ms, though the peak will vary in latency (delay between stimulus and response) from 250-500 ms or later depending upon the task.〔Polich, J. (2007). Updating P300: An integrative theory of P3a and P3b. Clinical Neurophysiology, 118(10), 2128-2148.〕 Amplitudes are typically highest on the scalp over parietal brain areas.〔Polich, J. (2007). Updating P300: An integrative theory of P3a and P3b. Clinical Neurophysiology, 118(10), 2128-2148.〕 The P3b has been a prominent tool used to study cognitive processes for several decades. More specifically, this ERP component has played a key role in cognitive psychology research on information processing. Generally speaking, improbable events will elicit a P3b, and the less probable the event, the larger the P3b.〔Donchin, E. (1981). "Presidential Address, 1980: Surprise!...Surprise?." Psychophysiology 18(5): 493-513.〕 However, in order to elicit a P3b, the improbable event must be related to the task at hand in some way (for example, the improbable event could be an infrequent target letter in a stream of letters, to which a subject might respond with a button press). The P3b can also be used to measure how demanding a task is on cognitive workload.〔Donchin, E. (1981). "Presidential Address, 1980: Surprise!...Surprise?." Psychophysiology 18(5): 493-513.〕 ==History== Early observations of the P3b were reported in the mid-1960s. In 1964, researchers Chapman and Bragdon.〔Chapman, R.M. & Bragdon, H.R. (1964). Evoked responses to numerical and non-numerical visual stimuli while problem solving. Nature, 203, 1155-1157.〕 found that ERP responses to visual stimuli differed depending on whether the stimuli had meaning or not. They showed subjects two kinds of visual stimuli: numbers and flashes of light. Subjects viewed these stimuli one at a time in a sequence. For every two numbers, the subjects were required to make simple decisions, such as telling which of the two numbers was numerically smaller or larger, which came first or second in the sequence, or whether they were equal. When examining evoked potentials to these stimuli (i.e., ERPs), Chapman and Bragdon found that both the numbers and the flashes elicited the expected sensory responses (e.g., visual N1 components), and that the amplitude of these responses varied in an expected fashion with the intensity of the stimuli. They also found that the ERP responses to the numbers, but not to the light flashes, contained a large positivity that peaked around 300 ms after the stimulus appeared.〔Chapman, R.M. & Bragdon, H.R. (1964). Evoked responses to numerical and non-numerical visual stimuli while problem solving. Nature, 203, 1155-1157.〕 They also noted that the amplitude of this positivity was not affected by the intensity of the stimulus. Chapman and Bragdon speculated that this differential response to the numbers, which came to be known as the P300 response, resulted from the fact that the numbers were meaningful to the participants, based on the task that they were asked to perform. In 1965, Sutton and colleagues published results from two experiments that further explored this late positivity. They presented subjects with either a cue that indicated whether the following stimulus would be a click or a flash, or a cue which required subjects to guess whether the following stimulus would be a click or a flash. They found that when subjects were required to guess what the following stimulus would be, the amplitude of the “late positive complex”〔Sutton, S., Braren, M., Zubin, J., & John, E.R. (1965). Evoked-Potential Correlates of Stimulus Uncertainty. Science, 150(3700), 1187-1188.〕 was larger than when they knew what the stimulus would be. In a second experiment,〔Sutton, S., Braren, M., Zubin, J., & John, E.R. (1965). Evoked-Potential Correlates of Stimulus Uncertainty. Science, 150(3700), 1187-1188.〕 they presented two cue types. For one cue there was a 2 in 3 chance that the following stimulus would be a click and a 1 in 3 chance that the following stimulus would be a flash. The second cue type had probabilities that were the reverse of the first. They found that the amplitude of the positive complex was larger in response to the less probable stimuli, or the one that only had a 1 in 3 chance of appearing. Another important finding from these studies is that this late positive complex was observed for both the clicks and flashes, indicating that the physical type of the stimulus (auditory or visual) did not matter.〔Sutton, S., Braren, M., Zubin, J., & John, E.R. (1965). Evoked-Potential Correlates of Stimulus Uncertainty. Science, 150(3700), 1187-1188.〕 In later studies published in 1967, Sutton and colleagues had subjects guess whether they would hear one click or two clicks.〔Sutton, S., Tueting, P., Zubin, J., & John, E.R. (1967). Information delivery and the sensory evoked potential. Science, 155, 1436-1439.〕 They observed a positivity around 300 ms after the second click occurred or would have occurred in the case of the single click. They also had subjects guess how long the interval between clicks might be, and the late positivity occurred 300 ms after the second click.〔Sutton, S., Tueting, P., Zubin, J., & John, E.R. (1967). Information delivery and the sensory evoked potential. Science, 155, 1436-1439.〕 This shows two important findings: first that this late positivity occurred when the uncertainty about the type of click was resolved, and second that even an absence of a stimulus, when it was relevant to the task, would elicit the late positive complex. These early studies encouraged the use of ERP methods to study cognition and provided a foundation for the extensive work on the P3b in the decades that followed.〔Bashore, T.R. & van der Molen, M.W. (1991). Discovery of the P300: A tribute. Biological Psychology, 32, 155-171.〕 Since the initial discovery of this ERP component, research has shown that the P300 is not a unitary phenomenon. Rather, we can distinguish between two subcomponents of the P300: the novelty P3, or P3a, and the classic P3, or P3b.〔Squires, N.K., Squires, K.C., & Hillyard, S.A. (1975). Two varieties of long-latency positive waves evoked by unpredictable auditory stimuli in man. Electroencephalography & Clinical Neurophysiology, 38, 387-401.〕 This article focuses on the P3b. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「P3b」の詳細全文を読む スポンサード リンク
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