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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク NPRL3 ： ウィキペディア英語版 NPRL3 Nitrogen permease regulator-like 3 is a protein that in humans is encoded by the NPRL3 gene. == Function == NPRL3 is a human protein of poorly understood function but has been associated with cancer. The most prominent function ascribed to Nprl3 to date is as part of the GATOR1 complex (with NPRL2 and DEPDC5) that inhibits the mechanistic target of rapamycin (mTOR) kinase-complex-1 (mTORC1) on the surface of the lysosome (equivalent of degradative vacuole in yeast) via an effect on the Rag GTPase complex. Additionally, Nprl3 has been shown to adjust cell metabolism via the TOR pathway, and this is important for development of the cardiovascular system in mammals.〔 Without this effect, spontaneous cell apoptosis would occur. A similar function for Nprl3 has been identified in the female reproductive system of ''Drosophila'' during times of protein scarcity. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「NPRL3」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.