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''N''-Methyltryptamine (NMT), or methyltryptamine, is a member of the tryptamine chemical class. It is an alkaloid, probably derived from L-tryptophan, that has been found in the bark, shoots and leaves of several plant species, including Virola, Acacia, Mimosa and Desmanthus often together with the related compounds ''N'',''N''-dimethyltryptamine (DMT) and 5-methoxy-''N'',''N''-dimethyltryptamine (5-MeO-DMT). It is also synthesized in the human body as a metabolic endproduct of the amino acid L-tryptophan.〔(Tryptophan metabolism )〕 It was found to be a natural trace component in human urine.〔Scand J Clin Lab Invest. 2001;61(7):547-56. Determination of potentially hallucinogenic N-dimethylated indoleamines in human urine by HPLC/ESI-MS-MS. Forsström T, Tuominen J, Karkkäinen J.〕 Orally administered NMT appears to produce no psychoactive effects, likely as a result of extensive first-pass metabolism.〔Foye's principles of medicinal chemistry By William O. Foye, Thomas L. Lemke, David A. Williams〕 However, it may become active upon combination with a MAOA inhibitor (MAOI).〔 By vaporization NMT shows activity at 50–100 mg, with a duration of 45–70 minutes; duration of visual effects 15–30 seconds. Effects are primarily non-visual.〔Shulgin & Shulgin "TIKHAL" 1997〕〔Nen 2011 - lecture presented EGA conference, Victoria. 4/12/2011.〕 == See also == * ''N''-Ethyltryptamine (NET) * ''N'',''N'',-Dimethyltryptamine (DMT) * ''Acacia confusa'' (a natural source of NMT, with other tryptamines, 1.63%. Buchanan et al. 2007) * ''Acacia obtusifolia'' (NMT up to 2/3 alkaloid content) * ''Acacia simplicifolia (synon. A. simplex) (1.44% NMT in bark, 0.29% twigs, Pouet ''et al.'' 1976) * ''Desmanthus Illinoensis'' (NMT major component seasonally) 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「N-Methyltryptamine」の詳細全文を読む スポンサード リンク
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