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Mederma
Mederma is a topical product used to improve scar appearance. It is a gel based on an onion extract and produced by Merz Pharmaceuticals〔(MEDERMA Skin Care for SCARS )〕 of Frankfurt, Germany. Mederma's marketing claims it can make scars "softer, smoother, and less noticeable".〔(MEDERMA Skin Care for SCARS Learning Center )〕 Generic versions are sold under the name cepalin.
== Effectiveness ==
One 2006 clinical trial found no statistically significant change in hypertrophic scar appearance from products of this type compared to the standard petrolatum emollient, while a 1999 pilot trial found an onion extract gel less effective than the petrolatum. In 2010 a 54-person trial funded by Merz found that an onion extract cream improved the appearance of stretch marks.〔WebMD. (Onion Cream Treats New Stretch Marks ).〕
Basic research and animal testing suggest the gel could be effective. A 1996 study into the therapeutic values of onion and garlic found that they may act as an anti-inflammatory and bacteriostatic〔K. Augusti, Therapeutic values of onion (Allium cepa L.) and garlic (Allium sativum L.), Indian J Exp Biol 34 (1996), pp. 634–640.〕 and in 2002, researchers found that Mederma improved collagen organization after injury in rabbits.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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